37131-87-6

  • Product Name:5-bromo-2-pyrimidinic acid
  • Molecular Formula:C5H3BrN2O2
  • Purity:99%
  • Molecular Weight:202.995
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Product Details

pd_meltingpoint:193-198℃

Purity:99%

Factory Sells Best Quality 5-bromo-2-pyrimidinic acid 37131-87-6 with GMP standards

  • Molecular Formula:C5H3BrN2O2
  • Molecular Weight:202.995
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:193-198℃ 
  • Refractive Index:1.627 
  • Boiling Point:419.698 °C at 760 mmHg 
  • PKA:2.85±0.10(Predicted) 
  • Flash Point:207.626 °C 
  • PSA:63.08000 
  • Density:1.941 g/cm3 
  • LogP:0.93730 

5-BROMOPYRIMIDINE-2-CARBOXYLIC ACID(Cas 37131-87-6) Usage

InChI:InChI=1/C5H3BrN2O2/c6-3-1-7-4(5(9)10)8-2-3/h1-2H,(H,9,10)

Company Profile

Bailong Pharmaceutical officially began operations in 2017, located in the High-tech Zone of Jinan City. It is a high-tech enterprise specializing in the research and production of chemical raw materials and advanced pharmaceutical intermediates, and has currently passed the GB/T 19001-2016/ISO 9001 quality management system certification standards. The company is dedicated to serving major pharmaceutical companies, fine chemical production units, large pharmaceutical research and development centers, and other users of pharmaceutical chemicals both domestically and internationally. It has established cooperation with nearly all of the top ten pharmaceutical companies in the country and hundreds of small and medium-sized biotechnology companies, providing specialized services such as the supply of commercial chemicals, technical research and development, production technology outsourcing, and customized chemicals. In 2020, it was included in the list of "Top Ten Suppliers of the Year" for certain A-share listed companies, reaching a long-term cooperation intention to help clients improve production capacity and development efficiency, and push the project to market at full speed.

 

Development History

  • 2020yearThe application for Shandong high-end pharmaceutical intermediates production base was successful, and it was officially put into operation in June 2022
  • 2021yearIn the first quarter, the growth rate reached a new high, with a year-on-year increase of 210%, achieving leapfrog growth in the new fiscal year
  • 2022yearIn December,the independent R&D laboratory building of Yinfeng Bio-City was put into operation to help product R&D and innovation.

37131-87-6 Relevant articles

Spirocyclic delta opioid receptor agonists for the treatment of pain: Discovery of N,N-diethyl-3-hydroxy-4-(spiro[chromene-2,4′-piperidine]-4- yl) benzamide (ADL5747)

Bourdonnec, Bertrand Le,Windh, Rolf T.,Leister, Lara K.,Zhou, Q. Jean,Ajello, Christopher W.,Gu, Minghua,Chu, Guo-Hua,Tuthill, Paul A.,Barker, William M.,Koblish, Michael,Wiant, Daniel D.,Graczyk, Thomas M.,Belanger, Serge,Cassel, Joel A.,Feschenko, Marina S.,Brogdon, Bernice L.,Smith, Steven A.,Derelanko, Michael J.,Kutz, Steve,Little, Patrick J.,Dehaven, Robert N.,DeHaven-Hudkins, Diane L.,Dolle, Roland E.

experimental part, p. 5685 - 5702 (2010/02/28)

Selective, nonpeptidic δ opioid receptor...

2-PHENYL SUBSTITUTED IMIDAZOL [4 , 5B] PYRIDINE/ PYRAZINE AND PURINE DERIVATIVES AS GLUCOKINASE MODULATORS

-

Page/Page column 102-103, (2010/11/25)

Compounds of Formula (I), wherein R1- R1...

SUBSTITUTED TRIAZOLE DERIVATIVES AS OXYTOCIN ANTAGONISTS

-

Page/Page column 87-88, (2010/02/11)

The present invention relates to a class...

37131-87-6 Process route

2-methylpyrimidine
5053-43-0

2-methylpyrimidine

5-bromo-2-pyrimidinecarboxylic acid
37131-87-6

5-bromo-2-pyrimidinecarboxylic acid

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: sodium acetate; acetic acid; bromine
2: AgNO3
With bromine; sodium acetate; silver nitrate; acetic acid;
 
5-bromopyrimidine-2-carbonitrile
38275-57-9

5-bromopyrimidine-2-carbonitrile

5-bromo-2-pyrimidinecarboxylic acid
37131-87-6

5-bromo-2-pyrimidinecarboxylic acid

Conditions
Conditions Yield
With sodium hydroxide; water; at 60 ℃; for 1h; Heating;
 
5-bromopyrimidine-2-carbonitrile; With sodium hydroxide; water; at 60 ℃; for 1h;
With hydrogenchloride; In water;
 

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