89581-38-4

  • Product Name:Methyl 5-bromo-2-pyrimidinyl formate
  • Molecular Formula:C6H5BrN2O2
  • Purity:99%
  • Molecular Weight:217.022
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Product Details

pd_meltingpoint:149°C(lit.)

Purity:99%

Top Quality Methyl 5-bromo-2-pyrimidinyl formate 89581-38-4 Hot Sell In Stock

  • Molecular Formula:C6H5BrN2O2
  • Molecular Weight:217.022
  • Vapor Pressure:0.000467mmHg at 25°C 
  • Melting Point:149°C(lit.) 
  • Refractive Index:1.558 
  • Boiling Point:314.4 °C at 760 mmHg 
  • PKA:-2.81±0.22(Predicted) 
  • Flash Point:143.9 °C 
  • PSA:52.08000 
  • Density:1.669 g/cm3 
  • LogP:1.02570 

Methyl-5-bromo-2 pyrimidine carboxylate(Cas 89581-38-4) Usage

InChI:InChI=1/C6H5BrN2O2/c1-11-6(10)5-8-2-4(7)3-9-5/h2-3H,1H3

Company Profile

Bailong Pharmaceutical officially began operations in 2017, located in the High-tech Zone of Jinan City. It is a high-tech enterprise specializing in the research and production of chemical raw materials and advanced pharmaceutical intermediates, and has currently passed the GB/T 19001-2016/ISO 9001 quality management system certification standards. The company is dedicated to serving major pharmaceutical companies, fine chemical production units, large pharmaceutical research and development centers, and other users of pharmaceutical chemicals both domestically and internationally. It has established cooperation with nearly all of the top ten pharmaceutical companies in the country and hundreds of small and medium-sized biotechnology companies, providing specialized services such as the supply of commercial chemicals, technical research and development, production technology outsourcing, and customized chemicals. In 2020, it was included in the list of "Top Ten Suppliers of the Year" for certain A-share listed companies, reaching a long-term cooperation intention to help clients improve production capacity and development efficiency, and push the project to market at full speed.

 

Development History

  • 2020yearThe application for Shandong high-end pharmaceutical intermediates production base was successful, and it was officially put into operation in June 2022
  • 2021yearIn the first quarter, the growth rate reached a new high, with a year-on-year increase of 210%, achieving leapfrog growth in the new fiscal year
  • 2022yearIn December,the independent R&D laboratory building of Yinfeng Bio-City was put into operation to help product R&D and innovation.

89581-38-4 Relevant articles

2-ARYLSULFONAMIDO-N-ARYLACETAMIDE DERIVATIZED STAT3 INHIBITORS

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Paragraph 00770; 00772, (2018/08/20)

The present disclosure provides pharmace...

CYCLOPROPYL FUSED THIAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE

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Page/Page column 328, (2016/04/20)

The present invention provides a new cla...

PERFLUORINATED CYCLOPROPYL FUSED 1,3-OXAZIN-2-AMINE COMPOUNDS AS BETA-SECRETASE INHIBITORS AND METHODS OF USE

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Page/Page column 185; 186, (2014/09/29)

PERFLUORINATED CYCLOPROPYL FUSED 1,3-OXA...

P2X7 MODULATORS

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Paragraph 0126; 0169; 0170, (2014/09/30)

The present invention is directed to a c...

89581-38-4 Process route

methanol
67-56-1

methanol

5-bromo-2-pyrimidinecarboxylic acid
37131-87-6

5-bromo-2-pyrimidinecarboxylic acid

5-bromopyrimidine-2-carboxylic acid methyl ester
89581-38-4

5-bromopyrimidine-2-carboxylic acid methyl ester

Conditions
Conditions Yield
With acetyl chloride; for 0.25h; Reflux;
67%
With acetyl chloride; for 0.25h; Reflux;
67%
With hydrogenchloride; at 0 - 20 ℃; for 18h;
57%
With triethylamine; at 0 - 20 ℃;
 
methanol
67-56-1

methanol

5-bromopyrimidine-2-carbonitrile
38275-57-9

5-bromopyrimidine-2-carbonitrile

5-bromopyrimidine-2-carboxylic acid methyl ester
89581-38-4

5-bromopyrimidine-2-carboxylic acid methyl ester

Conditions
Conditions Yield
With hydrogenchloride; In water; at 80 ℃; for 2h; Inert atmosphere;
71%

89581-38-4 Upstream products

  • 67-56-1
    67-56-1

    methanol

  • 37131-87-6
    37131-87-6

    5-bromo-2-pyrimidinecarboxylic acid

  • 38275-57-9
    38275-57-9

    5-bromopyrimidine-2-carbonitrile

  • 1013335-78-8
    1013335-78-8

    5-bromopyridine-2-carboxylic acid chloride

89581-38-4 Downstream products

  • 38275-60-4
    38275-60-4

    5-bromo-pyrimidine-2-carboxylic acid amide

  • 1294519-65-5
    1294519-65-5

    C12H12N4O4S

  • 1312312-95-0
    1312312-95-0

    methyl 5-[4-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyloxy)phenyl]-pyrimidine-2-carboxylate

  • 87362-30-9
    87362-30-9

    5-bromopyrimidine-2-carbohydrazide

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