6759-78-0
- Product Name：8-Hydroxyquinoline-2-carboxylic acid
- Molecular Formula：C10H6N2O
- Purity：99%
- Molecular Weight：170.17
Product Details
pd_meltingpoint:133-136 °C
Appearance:yellow to brown crystalline powder
Purity:99%
Purity 99% Min 8-Hydroxyquinoline-2-carboxylic acid 6759-78-0 Spot Supply with Safe Transportation
- Molecular Formula:C10H6N2O
- Molecular Weight:170.17
- Appearance/Colour:yellow to brown crystalline powder
- Vapor Pressure:4.62E-07mmHg at 25°C
- Melting Point:133-136 °C
- Refractive Index:1.702
- Boiling Point:402.7 °C at 760 mmHg
- PKA:8.92±0.10(Predicted)
- Flash Point:197.3 °C
- PSA：56.91000
- Density:1.36 g/cm3
- LogP:1.81208
8-HYDROXYQUINOLINE-2-CARBONITRILE(Cas 6759-78-0) Usage
InChI:InChI=1/C10H6N2O/c11-6-8-5-4-7-2-1-3-9(13)10(7)12-8/h1-5,13H
Company Profile
Bailong Pharmaceutical officially began operations in 2017, located in the High-tech Zone of Jinan City. It is a high-tech enterprise specializing in the research and production of chemical raw materials and advanced pharmaceutical intermediates, and has currently passed the GB/T 19001-2016/ISO 9001 quality management system certification standards. The company is dedicated to serving major pharmaceutical companies, fine chemical production units, large pharmaceutical research and development centers, and other users of pharmaceutical chemicals both domestically and internationally. It has established cooperation with nearly all of the top ten pharmaceutical companies in the country and hundreds of small and medium-sized biotechnology companies, providing specialized services such as the supply of commercial chemicals, technical research and development, production technology outsourcing, and customized chemicals. In 2020, it was included in the list of "Top Ten Suppliers of the Year" for certain A-share listed companies, reaching a long-term cooperation intention to help clients improve production capacity and development efficiency, and push the project to market at full speed.
Development History
- 2020yearThe application for Shandong high-end pharmaceutical intermediates production base was successful, and it was officially put into operation in June 2022
- 2021yearIn the first quarter, the growth rate reached a new high, with a year-on-year increase of 210%, achieving leapfrog growth in the new fiscal year
- 2022yearIn December,the independent R&D laboratory building of Yinfeng Bio-City was put into operation to help product R&D and innovation.
6759-78-0 Relevant articles
The Hiratani-double-Claisen rearrangement as a key step in the preparation of sequential bis(8-hydroxyquinoline) ligands
Albrecht, Markus,Osetska, Olga,Fr?hlich, Roland
, p. 924 - 926 (2006)
Symmetric and sequential isobutenylidene...
6759-78-0 Process route
-
- 46151-65-9
8-Hydroxy-1-methoxy-quinolinium
-
- 143-33-9,25596-52-5
sodium cyanide
-
- 6759-79-1
8-hydroxyquinoline-2-carboxamide
-
- 6759-78-0
8-hydroxyquinoline-2-carbonitrile
| Conditions | Yield |
|---|---|
|
In water;
|
-
- 6759-78-0
8-hydroxyquinoline-2-carbonitrile
-
- 591-51-5
phenyllithium
-
- 1009843-10-0
2-(amino(phenyl)methyl)quinolin-8-ol
| Conditions | Yield |
|---|---|
|
8-hydroxyquinoline-2-carbonitrile; phenyllithium; With sodium tetrahydroborate; In tetrahydrofuran; dibutyl ether; at -78 ℃;
With hydrogenchloride; In tetrahydrofuran; dibutyl ether; water;
|
50% |
|
Multi-step reaction with 2 steps
1: tetrahydrofuran; dibutyl ether / 2 h / -78 - 20 °C / Inert atmosphere
2: sodium tetrahydroborate / ethanol; tetrahydrofuran; dibutyl ether / 3 h / -78 - 20 °C / Inert atmosphere
With sodium tetrahydroborate; In tetrahydrofuran; ethanol; dibutyl ether;
|
6759-78-0 Upstream products
-
46151-65-9
8-Hydroxy-1-methoxy-quinolinium
-
143-33-9
sodium cyanide
6759-78-0 Downstream products
-
1571-30-8
8-hydroxy-quinoline-2-carboxylic acid
-
99248-68-7
2-cyano-8-hydroxy-5-nitroquinoline
-
220108-56-5
8-hydroxyquinoline-2-oxazoline
-
1009843-10-0
2-(amino(phenyl)methyl)quinolin-8-ol
Relevant Products
-
Methyl ortho hydroxy para aminobenzoateCAS：4136-97-4
-
6-Chloro-5-methyl-2-cyanopyridineCAS：875293-89-3
-
2-Cyano-5,6-dimethylpyridineCAS：59146-67-7
