152126-31-3
- Product Name：3-Fluoropyridine-2-carboxylic acid
- Molecular Formula：C6H4FNO2
- Purity：99%
- Molecular Weight：141.102
Product Details
pd_meltingpoint:154 °C
Purity:99%
Excellent chemical plant bulk supply 3-Fluoropyridine-2-carboxylic acid 152126-31-3
- Molecular Formula:C6H4FNO2
- Molecular Weight:141.102
- Vapor Pressure:0.00465mmHg at 25°C
- Melting Point:154 °C
- Refractive Index:1.541
- Boiling Point:265.2 °C at 760 mmHg
- PKA:2.71±0.10(Predicted)
- Flash Point:114.2 °C
- PSA：50.19000
- Density:1.419 g/cm3
- LogP:0.91890
3-FLUOROPYRIDINE-2-CARBOXYLIC ACID(Cas 152126-31-3) Usage
|
General Description |
3-Fluoropyridine-2-Carboxylic Acid is a fluorinated pyridine derivative. It is often used in scientific research, particularly in the field of organic chemistry, as a building block for the synthesis of more complex compounds. This chemical compound has unique properties due to the presence of a fluorine atom and carboxylic acid group. Its structure comprises a pyridine ring, a type of aromatic heterocyclic compound, with a fluorine atom attached at the 3-position and a carboxylic acid group at the 2-position. It is generally available as a light yellow to brown crystalline powder and has the molecular formula of C6H4FNO2. |
InChI:InChI=1/C6H4FNO2/c7-4-2-1-3-8-5(4)6(9)10/h1-3H,(H,9,10)
Company Profile
Bailong Pharmaceutical officially began operations in 2017, located in the High-tech Zone of Jinan City. It is a high-tech enterprise specializing in the research and production of chemical raw materials and advanced pharmaceutical intermediates, and has currently passed the GB/T 19001-2016/ISO 9001 quality management system certification standards. The company is dedicated to serving major pharmaceutical companies, fine chemical production units, large pharmaceutical research and development centers, and other users of pharmaceutical chemicals both domestically and internationally. It has established cooperation with nearly all of the top ten pharmaceutical companies in the country and hundreds of small and medium-sized biotechnology companies, providing specialized services such as the supply of commercial chemicals, technical research and development, production technology outsourcing, and customized chemicals. In 2020, it was included in the list of "Top Ten Suppliers of the Year" for certain A-share listed companies, reaching a long-term cooperation intention to help clients improve production capacity and development efficiency, and push the project to market at full speed.
Development History
- 2020yearThe application for Shandong high-end pharmaceutical intermediates production base was successful, and it was officially put into operation in June 2022
- 2021yearIn the first quarter, the growth rate reached a new high, with a year-on-year increase of 210%, achieving leapfrog growth in the new fiscal year
- 2022yearIn December,the independent R&D laboratory building of Yinfeng Bio-City was put into operation to help product R&D and innovation.
152126-31-3 Relevant articles
The discovery of potent small molecule cyclic urea activators of STING
Banerjee, Monali,Basu, Sourav,Ghosh, Rajib,Middya, Sandip,Pryde, David C.,Shrivastava, Ritesh,Surya, Arjun,Yadav, Dharmendra B.
supporting information, (2022/02/07)
STING mediates innate immune responses t...
Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides
Laqua, Katja,Klemm, Marcel,Richard-Greenblatt, Melissa,Richter, Adrian,Liebe, Linda,Huang, Tingting,Lin, Shuangjun,Guardia, Ana,Pérez-Herran, Esther,Ballell, Lluís,Av-Gay, Yossef,Imming, Peter
, p. 3166 - 3190 (2018/05/05)
In recent years, several small natural c...
SPECIFIC CARBOXAMIDES AS KCNQ2/3 MODULATORS
-
Page/Page column 38, (2014/06/23)
The invention relates to specific carbox...
Converting core compounds into building blocks: The concept of regiochemically exhaustive functionalization
Marzi, Elena,Bobbio, Carla,Cottet, Fabrice,Schlosser, Manfred
, p. 2116 - 2123 (2007/10/03)
In a model study, 3-fluorophenol and 3-f...
152126-31-3 Process route
-
- 372-47-4
3-Fluoropyridine
-
- 124-38-9,18923-20-1
carbon dioxide
-
- 152126-31-3
3-fluoro(pyridin-2-yl)carboxylic acid
| Conditions | Yield |
|---|---|
|
With 1,4-diaza-bicyclo[2.2.2]octane; n-butyllithium; In diethyl ether; hexane; at -75 ℃;
|
49% |
|
3-Fluoropyridine; With 1,4-diaza-bicyclo[2.2.2]octane; n-butyllithium; In diethyl ether; hexane; at -78 - -60 ℃; for 1h;
carbon dioxide; In diethyl ether; hexane; at -78 - -10 ℃; for 0.333333h;
|
1.2 g |
-
- 860296-21-5
4-chloro-3-fluoropyridine-2-carboxylic acid
-
- 152126-31-3
3-fluoro(pyridin-2-yl)carboxylic acid
| Conditions | Yield |
|---|---|
|
With hydrogen; ammonium formate; palladium on activated charcoal; In ethanol; for 6h;
|
89% |
152126-31-3 Upstream products
-
372-47-4
3-Fluoropyridine
-
124-38-9
carbon dioxide
-
860296-21-5
4-chloro-3-fluoropyridine-2-carboxylic acid
-
2546-56-7
4-chloro-3-fluoro-pyridine
152126-31-3 Downstream products
-
1086562-12-0
2-[2-[(3-fluoropyridine-2-carbonyl)-amino]-3-methoxyphenyl]-benzoxazole-4-carboxylic acid methyl ester
-
1254364-39-0
C30H36BFN4O7
-
886510-21-0
3-fluoro-2-(trifluoromethyl)pyridine
-
869108-35-0
methyl 3-fluoropyridine-2-carboxylate
Relevant Products
-
4-cyanopyridine monotrifluoroacetateCAS：29885-70-9
-
3-bromo-4-nitropyridineCAS：89364-04-5
-
6-Chloro-5-methyl-2-cyanopyridineCAS：875293-89-3
