218301-22-5
- Product Name：3-Cyano-4-fluorobenzaldehyde
- Molecular Formula：C8H4FNO
- Purity：99%
- Molecular Weight：149.124
Product Details
pd_meltingpoint:80-84 °C(lit.)
Purity:99%
99% Purity Commercial production 3-Cyano-4-fluorobenzaldehyde 218301-22-5 with Cheapest Price
- Molecular Formula:C8H4FNO
- Molecular Weight:149.124
- Melting Point:80-84 °C(lit.)
- Boiling Point:215.603 °C at 760 mmHg
- Flash Point:84.194 °C
- PSA：40.86000
- Density:1.26 g/cm3
- LogP:1.50988
2-FLUORO-5-FORMYLBENZONITRILE(Cas 218301-22-5) Usage
|
General Description |
2-Fluoro-5-formylbenzonitrile is a benzonitrile derivative. |
InChI:InChI=1S/C8H4FNO/c9-8-2-1-6(5-11)3-7(8)4-10/h1-3,5H
Company Profile
Bailong Pharmaceutical officially began operations in 2017, located in the High-tech Zone of Jinan City. It is a high-tech enterprise specializing in the research and production of chemical raw materials and advanced pharmaceutical intermediates, and has currently passed the GB/T 19001-2016/ISO 9001 quality management system certification standards. The company is dedicated to serving major pharmaceutical companies, fine chemical production units, large pharmaceutical research and development centers, and other users of pharmaceutical chemicals both domestically and internationally. It has established cooperation with nearly all of the top ten pharmaceutical companies in the country and hundreds of small and medium-sized biotechnology companies, providing specialized services such as the supply of commercial chemicals, technical research and development, production technology outsourcing, and customized chemicals. In 2020, it was included in the list of "Top Ten Suppliers of the Year" for certain A-share listed companies, reaching a long-term cooperation intention to help clients improve production capacity and development efficiency, and push the project to market at full speed.
Development History
- 2020yearThe application for Shandong high-end pharmaceutical intermediates production base was successful, and it was officially put into operation in June 2022
- 2021yearIn the first quarter, the growth rate reached a new high, with a year-on-year increase of 210%, achieving leapfrog growth in the new fiscal year
- 2022yearIn December,the independent R&D laboratory building of Yinfeng Bio-City was put into operation to help product R&D and innovation.
218301-22-5 Relevant articles
Novel indazole derivatives, and use thereof
-
Paragraph 0112-0124, (2019/08/12)
The present invention refers to novel in...
FeCl3·6H2O/acetaldehyde, a versatile system for the deprotection of ketals and acetals via a transacetalization process
Schiavo, Lucie,Jeanmart, Lo?c,Lanners, Steve,Choppin, Sabine,Hanquet, Gilles
, p. 1421 - 1424 (2017/02/23)
Mild and efficient catalytic deprotectio...
HETEROCYCLIC DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF
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Paragraph 0137; 0138, (2013/09/12)
Disclosed are heterocyclic derivatives, ...
HETEROCYCLIC DERIVATES，PREPARATION PROCESSES AND MEDICAL USES THEREOF
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Page/Page column 22, (2012/06/16)
Disclosed are heterocyclic derivatives, ...
218301-22-5 Process route
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copper(l) cyanide
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- 77771-02-9
3-bromo-4-fluorobenzaldehyde
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- 218301-22-5
2-fluoro-5-formylbenzonitrile
| Conditions | Yield |
|---|---|
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copper(l) cyanide; 3-bromo-4-fluorobenzaldehyde; In 1-methyl-pyrrolidin-2-one; at 170 ℃; for 24h;
With celite; In 1-methyl-pyrrolidin-2-one; at 80 ℃; for 1h;
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100% |
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In 1-methyl-pyrrolidin-2-one; at 170 ℃; for 24h;
|
100% |
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In 1-methyl-pyrrolidin-2-one; at 170 ℃;
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65.4% |
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In 1-methyl-pyrrolidin-2-one; at 170 ℃; for 24h;
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52% |
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In 1-methyl-pyrrolidin-2-one; at 25 - 170 ℃;
|
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- 920-39-8
isopropylmagnesium bromide
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- 179897-89-3
5-Bromo-2-fluoro-benzonitrile
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- 218301-22-5
2-fluoro-5-formylbenzonitrile
| Conditions | Yield |
|---|---|
|
isopropylmagnesium bromide; 5-Bromo-2-fluoro-benzonitrile; In tetrahydrofuran; at 0 - 20 ℃; for 2h; Cooling with ice;
N,N-dimethyl-formamide; In tetrahydrofuran; for 3h;
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218301-22-5 Upstream products
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544-92-3
copper(I) cyanide
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77771-02-9
3-bromo-4-fluorobenzaldehyde
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218301-21-4
2-fluoro-5-bis-bromomethylbenzonitrile
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180302-35-6
5-bromomethyl-2-fluorobenzonitrile
218301-22-5 Downstream products
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227609-85-0
2-fluoro-5-(hydroxymethyl)benzonitrile
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310424-28-3
(Z)-3-(3-Cyano-4-fluoro-phenyl)-acrylic acid methyl ester
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1379825-89-4
(Z)-2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrle
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676602-31-6
3-cyano-4-fluorobenzoic acid methyl ester
Relevant Products
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4-cyanopyridine monotrifluoroacetateCAS：29885-70-9
-
3-bromopyridineCAS：626-55-1
-
3-bromo-4-nitropyridineCAS：89364-04-5
