
97483-77-7
- Product Name:2-cyano-5-bromopyridine
- Molecular Formula:C6H3BrN2
- Purity:99%
- Molecular Weight:183.007
Product Details
pd_meltingpoint:128-132 °C(lit.)
Appearance:light yellow cryst
Purity:99%
Quality Manufacturer Supply High Purity 99% 2-cyano-5-bromopyridine 97483-77-7 with Reasonable Price
- Molecular Formula:C6H3BrN2
- Molecular Weight:183.007
- Appearance/Colour:light yellow cryst
- Vapor Pressure:0.0124mmHg at 25°C
- Melting Point:128-132 °C(lit.)
- Refractive Index:1.611
- Boiling Point:260.3 °C at 760 mmHg
- PKA:-2.68±0.10(Predicted)
- Flash Point:111.2 °C
- PSA:36.68000
- Density:1.72 g/cm3
- LogP:1.71578
5-Bromo-2-pyridinecarbonitrile(Cas 97483-77-7) Usage
InChI:InChI=1/C6H3BrN2/c7-5-1-2-6(3-8)9-4-5/h1-2,4H
Company Profile
Bailong Pharmaceutical officially began operations in 2017, located in the High-tech Zone of Jinan City. It is a high-tech enterprise specializing in the research and production of chemical raw materials and advanced pharmaceutical intermediates, and has currently passed the GB/T 19001-2016/ISO 9001 quality management system certification standards. The company is dedicated to serving major pharmaceutical companies, fine chemical production units, large pharmaceutical research and development centers, and other users of pharmaceutical chemicals both domestically and internationally. It has established cooperation with nearly all of the top ten pharmaceutical companies in the country and hundreds of small and medium-sized biotechnology companies, providing specialized services such as the supply of commercial chemicals, technical research and development, production technology outsourcing, and customized chemicals. In 2020, it was included in the list of "Top Ten Suppliers of the Year" for certain A-share listed companies, reaching a long-term cooperation intention to help clients improve production capacity and development efficiency, and push the project to market at full speed.
Development History
- 2020yearThe application for Shandong high-end pharmaceutical intermediates production base was successful, and it was officially put into operation in June 2022
- 2021yearIn the first quarter, the growth rate reached a new high, with a year-on-year increase of 210%, achieving leapfrog growth in the new fiscal year
- 2022yearIn December,the independent R&D laboratory building of Yinfeng Bio-City was put into operation to help product R&D and innovation.
97483-77-7 Relevant articles
Preparation method of 2-cyano-5-bromopyridine
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Paragraph 0035-0038; 0041-0045, (2021/11/06)
The invention provides a preparation met...
2 - Cyano -5 - bromo pyridine preparation method
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Paragraph 0025-0092, (2019/04/10)
The invention belongs to the field of or...
C?H Cyanation of 6-Ring N-Containing Heteroaromatics
Elbert, Bryony L.,Farley, Alistair J. M.,Gorman, Timothy W.,Johnson, Tarn C.,Genicot, Christophe,Lallemand, Bénédicte,Pasau, Patrick,Flasz, Jakub,Castro, José L.,MacCoss, Malcolm,Paton, Robert S.,Schofield, Christopher J.,Smith, Martin D.,Willis, Michael C.,Dixon, Darren J.
supporting information, p. 14733 - 14737 (2017/10/07)
Heteroaromatic nitriles are important co...
A oxazolidinone compounds of preparation method (by machine translation)
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Paragraph 0048, (2017/05/12)
The invention provides a oxazolidinone c...
97483-77-7 Process route
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- 624-28-2
2,5-dibromopyridine

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- 97483-77-7
2-Cyano-5-bromopyridine
Conditions | Yield |
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Multi-step reaction with 2 steps
1.1: 85 percent / NaI; AcCl / acetonitrile / 3 h / Heating
2.1: iPrMgCl / CH2Cl2; tetrahydrofuran / 0.75 h / 0 °C
2.2: 82 percent / CH2Cl2; tetrahydrofuran / 2 h / 20 °C
With isopropylmagnesium chloride; acetyl chloride; sodium iodide; In tetrahydrofuran; dichloromethane; acetonitrile;
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Multi-step reaction with 2 steps
1.1: n-butyllithium / toluene / 2 h / -78 °C
1.2: toluene / 1 h / -78 °C
2.1: POCl3 / toluene / 5 h / 110 °C
With n-butyllithium; trichlorophosphate; In toluene;
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In N-methyl-acetamide;
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With zinc(II) cyanide; zinc; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In DMF (N,N-dimethyl-formamide); for 5h; Heating / reflux;
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- 624-28-2
2,5-dibromopyridine

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copper(l) cyanide

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- 97483-77-7
2-Cyano-5-bromopyridine
Conditions | Yield |
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With sodium cyanide; In N,N-dimethyl-formamide; at 150 ℃; for 7h; Inert atmosphere;
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70% |
97483-77-7 Upstream products
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2402-97-3
3-bromopyridine N-oxide
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7677-24-9
trimethylsilyl cyanide
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647826-69-5
5-bromo-pyridine-2-carboxylic acid tert-butylamide
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624-28-2
2,5-dibromopyridine
97483-77-7 Downstream products
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380380-60-9
2-(1,2,3,4-tetrazol-5-yl)-5-bromopyridine
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741709-63-7
2-cyanopyridine-5-boronic acid pinacol ester
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30766-11-1
5-bromoisonicotinic acid
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944718-22-3
1-(5-bromopyridin-2-yl)cyclopropanamine
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-
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