3783-38-8
- Product Name：4-(methoxycarbonyl)pyridine 1-oxide
- Molecular Formula：C7H7 N O3
- Purity：99%
- Molecular Weight：153.137
Product Details
pd_meltingpoint:116.5-118.5 °C(Solv: ethyl acetate (141-78-6))
Purity:99%
Reliable Quality 4-(methoxycarbonyl)pyridine 1-oxide 3783-38-8 Hot Sale with Chinese Manufacturer
- Molecular Formula:C7H7 N O3
- Molecular Weight:153.137
- Vapor Pressure:8.59E-05mmHg at 25°C
- Melting Point:116.5-118.5 °C(Solv: ethyl acetate (141-78-6))
- Boiling Point:340.5°Cat760mmHg
- PKA:-0.41±0.10(Predicted)
- Flash Point:159.7°C
- PSA：51.76000
- Density:1.2g/cm3
- LogP:0.90170
METHYLISONICOTINATE-N-OXIDE(Cas 3783-38-8) Usage
InChI:InChI=1/C7H7NO3/c1-11-7(9)6-2-4-8(10)5-3-6/h2-5H,1H3
Company Profile
Bailong Pharmaceutical officially began operations in 2017, located in the High-tech Zone of Jinan City. It is a high-tech enterprise specializing in the research and production of chemical raw materials and advanced pharmaceutical intermediates, and has currently passed the GB/T 19001-2016/ISO 9001 quality management system certification standards. The company is dedicated to serving major pharmaceutical companies, fine chemical production units, large pharmaceutical research and development centers, and other users of pharmaceutical chemicals both domestically and internationally. It has established cooperation with nearly all of the top ten pharmaceutical companies in the country and hundreds of small and medium-sized biotechnology companies, providing specialized services such as the supply of commercial chemicals, technical research and development, production technology outsourcing, and customized chemicals. In 2020, it was included in the list of "Top Ten Suppliers of the Year" for certain A-share listed companies, reaching a long-term cooperation intention to help clients improve production capacity and development efficiency, and push the project to market at full speed.
Development History
- 2020yearThe application for Shandong high-end pharmaceutical intermediates production base was successful, and it was officially put into operation in June 2022
- 2021yearIn the first quarter, the growth rate reached a new high, with a year-on-year increase of 210%, achieving leapfrog growth in the new fiscal year
- 2022yearIn December,the independent R&D laboratory building of Yinfeng Bio-City was put into operation to help product R&D and innovation.
3783-38-8 Relevant articles
Controlling the optical and catalytic properties of artificial metalloenzyme photocatalysts using chemogenetic engineering
Gu, Yifan,Lewis, Jared C.,Liu, Bingqing,Sahoo, Dipankar,Zubi, Yasmine S.
, p. 1459 - 1468 (2022/02/14)
Visible light photocatalysis enables a b...
A Photosensitizer-Free Radical Cascade for Synthesizing CF3-Containing Polycyclic Quinazolinones with Visible Light
Hu, Qiang,Yu, Wan-Lei,Luo, Yong-Chun,Hu, Xiu-Qin,Xu, Peng-Fei
supporting information, p. 1493 - 1501 (2022/02/07)
Herein, we report an efficient photoindu...
Visible-Light-Induced ortho-Selective Migration on Pyridyl Ring: Trifluoromethylative Pyridylation of Unactivated Alkenes
Jeon, Jinwon,He, Yu-Tao,Shin, Sanghoon,Hong, Sungwoo
supporting information, p. 281 - 285 (2019/11/26)
The photocatalyzed ortho-selective migra...
Photoredox generation of the trifluoromethyl radical from borate complexes: Via single electron reduction
Smirnov, Vladimir O.,Maslov, Anton S.,Kokorekin, Vladimir A.,Korlyukov, Alexander A.,Dilman, Alexander D.
supporting information, p. 2236 - 2239 (2018/03/06)
A method for the generation of the CF3 r...
3783-38-8 Process route
-
- 2459-09-8
4-pyridinecarboxylic acid, methyl ester
-
- 3783-38-8
methyl isonicotinate N-oxide
| Conditions | Yield |
|---|---|
|
4-pyridinecarboxylic acid, methyl ester; With dihydrogen peroxide; methyltrioxorhenium(VII); In dichloromethane; water; at 20 ℃; for 18h;
With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 2h;
|
99% |
|
With bis-trimethylsilanyl peroxide; per-rhenic acid; In dichloromethane; water; at 24 ℃; for 6h;
|
98% |
|
With dihydrogen peroxide; methyltrioxorhenium(VII); In dichloromethane; water; at 24 ℃; for 17h;
|
98% |
|
With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;
|
97% |
|
With dihydrogen peroxide; methyltrioxorhenium(VII); In dichloromethane; water; at 20 ℃; Inert atmosphere;
|
95% |
|
With dihydrogen peroxide; acetic acid; at 70 ℃; Solvent;
|
95.2% |
|
With dihydrogen peroxide; In acetic acid; at 70 ℃; Solvent;
|
95.2% |
|
With dihydrogen peroxide; methyltrioxorhenium(VII); In dichloromethane; at 24 ℃; for 12h; Inert atmosphere;
|
93% |
|
With dihydrogen peroxide; acetic acid; at 70 ℃;
|
92% |
|
4-pyridinecarboxylic acid, methyl ester; With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 6h; Inert atmosphere; Reflux;
With potassium carbonate; In dichloromethane; Inert atmosphere;
|
91% |
|
With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
|
78% |
|
With dihydrogen peroxide; acetic acid;
|
70% |
|
With dihydrogen peroxide; In water; acetic acid;
|
65% |
|
With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 3h; Sealed tube;
|
46% |
|
With Perbenzoic acid; In 1,4-dioxane; water; at 20 ℃; Thermodynamic data; Kinetics; Mechanism; other temp. (25, 30 deg C); ΔS(excit.);
|
|
|
With dihydrogen peroxide; acetic acid;
|
|
|
4-pyridinecarboxylic acid, methyl ester; With dihydrogen peroxide; methyltrioxorhenium(VII); In dichloromethane; at 20 ℃;
manganese(IV) oxide; In dichloromethane; at 20 ℃; for 1h;
|
|
|
With 3-chloro-benzenecarboperoxoic acid; In acetonitrile; at 95 ℃; under 6000.6 Torr; Flow reactor;
|
|
|
With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 18h;
|
|
|
4-pyridinecarboxylic acid, methyl ester; With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃; for 6h;
With triphenylphosphine; In dichloromethane; at 20 ℃; for 4h;
|
-
- 67-56-1
methanol
-
- 13602-12-5
Isonicotinic acid N-oxide
-
- 3783-38-8
methyl isonicotinate N-oxide
| Conditions | Yield |
|---|---|
|
With diazomethyl-trimethyl-silane; In hexane; at 0 ℃; for 1h;
|
97% |
|
With thionyl chloride; at 20 ℃; for 2h;
|
72% |
|
With sulfuric acid; In toluene; Reflux; Dean-Stark;
|
45% |
3783-38-8 Upstream products
-
2459-09-8
4-pyridinecarboxylic acid, methyl ester
-
67-56-1
methanol
-
13602-12-5
Isonicotinic acid N-oxide
-
16357-59-8
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
3783-38-8 Downstream products
-
58481-11-1
methyl 2-chloroisonicotinate
-
89937-77-9
methyl 2-hydroxypyridine-4-carboxylate
-
2459-09-8
4-pyridinecarboxylic acid, methyl ester
-
94413-64-6
2-Cyano-4-carbomethoxypyridine
Relevant Products
-
Methyl ortho hydroxy para aminobenzoateCAS：4136-97-4
-
4-methoxy-2-nitro-1-phenoxybenzene (Impurity 5 of Eramod)CAS：84594-95-6
-
5-methoxy-2-phenoxyaniline (Emorad Impurity 6)CAS：76838-72-7
