1678-49-5
- Product Name：3-bromo-4-nitropyridine oxide
- Molecular Formula：C5H3BrN2O3
- Purity：99%
- Molecular Weight：218.994
Product Details
pd_meltingpoint:152-154 °C
Appearance:yellow crystalline powder
Purity:99%
Chinese Factory Supply Wholesale 3-bromo-4-nitropyridine oxide 1678-49-5 with Cheap Price
- Molecular Formula:C5H3BrN2O3
- Molecular Weight:218.994
- Appearance/Colour:yellow crystalline powder
- Vapor Pressure:4.99E-06mmHg at 25°C
- Melting Point:152-154 °C
- Refractive Index:1.666
- Boiling Point:393 °C at 760 mmHg
- PKA:-2.19±0.10(Predicted)
- Flash Point:191.5 °C
- PSA：71.28000
- Density:1.98 g/cm3
- LogP:2.30900
3-BROMO-4-NITROPYRIDINE N-OXIDE(Cas 1678-49-5) Usage
InChI:InChI=1/C5H3BrN2O3/c6-4-3-7(9)2-1-5(4)8(10)11/h1-3H
Company Profile
Bailong Pharmaceutical officially began operations in 2017, located in the High-tech Zone of Jinan City. It is a high-tech enterprise specializing in the research and production of chemical raw materials and advanced pharmaceutical intermediates, and has currently passed the GB/T 19001-2016/ISO 9001 quality management system certification standards. The company is dedicated to serving major pharmaceutical companies, fine chemical production units, large pharmaceutical research and development centers, and other users of pharmaceutical chemicals both domestically and internationally. It has established cooperation with nearly all of the top ten pharmaceutical companies in the country and hundreds of small and medium-sized biotechnology companies, providing specialized services such as the supply of commercial chemicals, technical research and development, production technology outsourcing, and customized chemicals. In 2020, it was included in the list of "Top Ten Suppliers of the Year" for certain A-share listed companies, reaching a long-term cooperation intention to help clients improve production capacity and development efficiency, and push the project to market at full speed.
Development History
- 2020yearThe application for Shandong high-end pharmaceutical intermediates production base was successful, and it was officially put into operation in June 2022
- 2021yearIn the first quarter, the growth rate reached a new high, with a year-on-year increase of 210%, achieving leapfrog growth in the new fiscal year
- 2022yearIn December,the independent R&D laboratory building of Yinfeng Bio-City was put into operation to help product R&D and innovation.
1678-49-5 Relevant articles
An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans
Huang, Ya-Yao,Chiu, Ming-Jang,Yen, Ruoh-Fang,Tsai, Chia-Ling,Hsieh, Hao-Yu,Chiu, Ching-Hung,Wu, Chi-Han,Hsin, Ling-Wei,Tzen, Kai-Yuan,Cheng, Cheng-Yi,Ma, Kuo-Hsing,Shiue, Chyng-Yann
, (2019/08/01)
[18F]T807 is a potent tau protein imagin...
N-(3-Arylaminopyridin-4-yl)alkanesulfonamides as pyridine analogs of nimesulide: Cyclooxygenases inhibition, anti-inflammatory studies and insight on metabolism
Renard, Jean-Fran?ois,Lecomte, Frédéric,Hubert, Philippe,De Leval, Xavier,Pirotte, Bernard
, p. 12 - 22 (2014/02/14)
Nimesulide, a COX-2 preferential inhibit...
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Wang,Li,Ye,Guo,Jia
, p. 4632 - 4636 (2013/07/25)
The dicationic carbazole compound, 3,6-d...
SUBSTITUTED BICYCLIC HETEROARYL COMPOUNDS AS mPGES-1 INHIBITORS
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Page/Page column 36, (2013/03/28)
The present invention relates to bicycli...
1678-49-5 Process route
-
- 2402-97-3
3-bromopyridine N-oxide
-
- 39856-50-3
5-bromo2-nitropyridine
-
- 1678-49-5
3-Bromo-4-nitropyridine N-oxide
| Conditions | Yield |
|---|---|
|
With sulfuric acid; nitric acid; at 0 - 90 ℃; for 5h;
|
49.1% 5.7% |
-
- 626-55-1,163928-56-1
3-Bromopyridine
-
- 39856-50-3
5-bromo2-nitropyridine
-
- 1678-49-5
3-Bromo-4-nitropyridine N-oxide
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: dihydrogen peroxide / acetic acid / 48 h / 80 °C
2: nitric acid; sulfuric acid / 5 h / 0 - 90 °C
With sulfuric acid; dihydrogen peroxide; nitric acid; In acetic acid;
|
1678-49-5 Upstream products
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2402-97-3
3-bromopyridine N-oxide
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63785-86-4
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626-55-1
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-
462-08-8
pyridin-3-ylamine
1678-49-5 Downstream products
-
13534-98-0
3-bromopyridin-4-amine
-
781-55-5
4-nitro-3-(piperidin-1-yl)pyridine 1-oxide
-
128864-00-6
4-nitro-2-(2-oxocyclohexyl)-3-piperidinopyridine
-
155561-25-4
4-benzyl-4'-nitro-3,3'-oxybispyridine 1'-oxide
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